The following is a translation of the instruction slip included with pharmaceutical grade phenibut dispensed at a Belarusian pharmacy, which lists directions for use, effects, indications etc. I wanted to do this for a long time, because in the West the medical establishment knows very little about phenibut and cannot recommend it for medical reasons, so hopefully, those who can benefit from it will have at least some medical information. I will further improve the precision of translation of certain medical terms as I work on it more. Wish I could include a scanned copy of original and the box itself but I guess I can't...
Instruction (information for patients on medical use of the drug Phenibut
Ratified by Ministry of Health of the Republic of Belarus on 13th of July, 2010.
Registration number 10/06/118
Trade name: Phenibut
International unpatented name: Phenibut
Release form: tablets
Description: Every tablet contains:
Active Chemical(s): Phenibut (250 mg) Non-medicinal ingredients: Monohydrous lactose, calcium stearate, potato starch
Pharmacological group: Nootropic drugs. GABA derivatives. Anxiolytics ATC code: N05BX; N06BX
Pharmacological Qualities
Nootropic drug. Improves functioning of the brain through normalization of tissue metabolism and influence on blood circulation in the brain (increases voluminous and linear velocity of blood circulation in the brain, lessens the stress on blood vessels in the brain, improves micro capillary circulation, has an anti-aggregate effect.
Helps lessen or removes the feeling of anxiety, subjective experience of panic, stress and fear response, normalizes sleep, has some alleviating effect on muscle cramps. Decreases asthenia and vaso-vegetative symptoms (including headache, sensation of heaviness in the head, sleep disturbances, irritability, emotional lability). Improves mental functioning.
Improves psychological factors (attention, memory, speed and precision of sensory-motor reactions). Prolonged use helps increase mental and physical workload, improves memory, helps maintain healthy sleep cycle. Improves functionality of patients with mobility and speech disorders.
Asthenic symptoms in patients usually improve within the first few days of use, helps boost interest and motivation without sedation or stimulation. Administered to brain trauma rehabilitation patients, as shown to increase quantities of mitochondria in perifocal regions and improve overall bioenergetic functioning of the telencephalon. Prescribed in cases of neurogenic defects of heart and stomach; normalizes peroxidation of lipids.
Does not cause excessive tiredness in the elderly.
Improves microcirculation in the tissues of the eye, decreases the CNS depressant action of ethanol. Has limited toxicity
PRESCRIBED FOR THE FOLLOWING CONDITIONS
Asthenic and neurotic psychological states, generalized anxiety and panic states, fear, OCD-type neurosis, psychopathy*, stuttering and twitches in children. Sleep disorders and persistent nightmares in the elderly. Prophylaxis of anticipation anxiety in patients awaiting a surgical intervention or invasive diagnostic procedures.
Meniere's disease, dizziness associated with vestibular disorders of the inner ear of various etiology (autogenic labyrinthitis, impairment of vascular functioning and inner ear trauma).
Also prescribed as an aid in maintenance of alcoholic abstinence syndrome. The drug must be used in combination with approved pharmaceutical means of Delirium Tremens maintenance.
DIRECTIONS FOR USE
To be taken by mouth, after a meal. Adults are prescribed 250-500 mg 3 times a day. If the treatment necessitates a higher dose it can be increased to a maximum of 2500 mg (a day). Children under 3 years of age are prescribed 50-100 mg, 3 times daily. Children between ages of 8 and 14 are prescribed 250 mg, 3 times daily. Maximal single dose (!) Adults – 750 mg, elderly patients (60 y.o. or older), - 500 mg, children under 8 – 150 mg, children 8-14 y.o. – 250 mg.
For management of alcohol abstinence symptoms,in the first days of treatment the dose should be 250-500 mg 3 times during the day, with additional 750 mg before bed. The dose must however begradually lowered to maximum adult daily amount during the course of treatment.
For management of Meniere’s disease: During flare ups: 750 mg 3-4 times every 24 hours. To be continued for a period of 5-7 days. As vestibular disturbance symptoms begin to subside, - 250-500 mg every 24 hours during the course of 5-7 days and finally tapered to 250 mg once every 24 hours, and administered for another 7-10 days.
Treatment of dizziness caused by dysfunction of vestibular analyzer of vascular or trauma related origin, - 250 mg 3 times every 24 hours. Continue taking over the course of 12 days
For prophylaxis of motion sickness: 250-500 mg, to be taken once, 1 hour before the planned trip. (Effectiveness is dose-dependent).
SIDE EFFECTS
Increase in irritability, hyper excitation, apprehensiveness , headache, dizziness, lethargy, nausea (in the beginning of treatment), allergic reactions (hives, itching).
OVERDOSE
Symptoms: pronounced lethargy, nausea, vomiting, fatty dystrophy of liver (when taken in excess of 7 grams), eosinophilia, low arterial blood pressure, kidney dysfunction.
Treatment: Gastric lavage, activated charcoal, symptomatic treatment.
OTHER CONSIDERATIONS
During a long course of treatment with phenibut it is necessary to conduct liver function tests (peripheral blood analysis). Phenibut has low effectiveness in pronounced symptoms of severe sea sickness such as continuous vomiting and dizziness.
PRECAUTIONARY MEASURES
During treatment it is advisable to abstain from potentially dangerous types of activity which demand increased attention.
DRUG INTERACTIONS
Prolongs and potentiates the action of sleep medications, narcotic analgesics, anti-epileptic, antipsychotic and anti-parkinsonian medications.
Not to be taken in combination with alcohol
STORAGE INSTRUCTIONS
To be stored in a place protected from moisture and light, below 25 degrees Celcius. To be kept in a place inaccessible to small children.
SHELF LIFE
3 years. Not to be used after expiry date posted on the package
PACKAGING
10 tablets in rectangular blister pack. 1, 2 or 5 rectangular blister packs including instruction slip are placed in single cardboard packaging box.
Le récréatif c'est bien ~
