There are lots of cycles: sociological, economical, climatological, hormonal, respiratory, solar, lunar and planetary cycles, binary star cycles, and many, many more from the smallest level to the largest.
The question now is whether some or all of these cycles are interrelated. The question is whether the cycles all function separate from eachother, or in harmony. Is the universe (matter and consciousness) built like a machine with all the wheels turning in sync, or is it rather just chaos?
If you believe the universe is chaos and nothing but chaos, you cannot take the beliefs surrounding 2012 seriously.
If you believe the universe is a composite of several cycles or patterns, you must take into account the possibility that some cycles return to a definable and scientifically discernable point (for example the vernal equinox or the first day of menstruation).
If you believe that there are several cycles with discernable return points, you cannot say 2012 is the only significant year. There's going to be many significant years, for example the years in which the astrological ages change, the year in which a sun spot cycle reaches its 11-year peak (or low) etc. And so the ancients celebrated lots of these points: eclipses, equinoxes, the Full Moon etc. In other words, they celebrated both yearly (or monthly) cycles as well as write about/predict important points of long term cycles such as the change of the astrological ages, particular planetary alignments etc.
It's important to remain aware of the fact that historically no turning point of a cycle has ever created havoc or heaven on that particular day. On the day of a solar eclipse nothing may seem to happen, although there are sometimes strong earthquakes in the 3 days following it. On the day of the vernal equinox there's no abrupt change from snow to butterflies. Similarly the world will not change radically in 2012, let alone December of that year, and much less the 21st. The change is happening now (just like it usually gets warmer by the end of February, weeks before the spring equinox), and it will continue happening after 2012.
So to recapitulate, if someone thinks 2012 is hogwash, they are in fact saying a relationship between cycles is imaginary and that there is no relationship between microcosmos and macrocosmos. This view resonates well with paradigms like the Big Bang and Darwin theories.
Those intrigued by the 2012 enigma may also believe creation started with some sort of bang, and that on this planet mutation, evolution and natural selection have played a part, but they recognize that it's not a random, chaotic process. There is an order and a purpose behind it all. The order is that harmony between larger and smaller cycles, and the grand purpose may be anything from "to create planets on which life may develop (i.e. DNA may proliferate), within which human beings may evolve to become aware of themselves and the universe."
According to the last view, everything was meant to be: the stone age, the Roman Empire, the British empire, the USA, and all the current struggles and revelations. The Internet was meant to be, Mozart was meant to be, Vietnam was meant to be, LSD and MDMA were meant to be.
And what is it all heading towards? No one can say. I don't believe any process will end in 2012, but it's one of those points in time that are significant from a cyclical point of view.
Notice the number 2012 is not going to make anything, just like the digit 0:00 is not creating the darkness at midnight. Neither is the clock creating the darkness. The digits and hands of the clock are simply the markers of processes in the external world. Similarly 2012 is simply a marker of processes going on in the world right now (people questioning the war on drugs, people abandoning monotheism, the 9/11 truth movement). So I agree with GOD that whatever is going to happen has nothing to do with 2012 (it has to do with the efforts of Erowid, MAPS and all of us). But it may very well be in and around 2012 that significant breakthroughs are going to occur.