an ice cold water extraction of "the deadly claviceps purpurea" would yield a substantial amount of the water soluble akaloid ergonovine (another name for ergometrine) and only trace amounts of lsa.....this ice cold water extraction would leave behind the toxic non-water soluble alkaloids of the ergopeptines/ergotoxine group. In other words, your ice cold water extraction of claviceps purpurea ergot will contain only substantial amounts of ergonovine and only trace amounts of lsa, it will contain no poisonous ergotoxic alkaloids, as those alkaloids are all NON-WATER SOLUBLE.
Years ago, b.c. consumed an ice cold water coffee filtered extract of 1.75 grams of claviceps purpurea that he found in the Tahoma mountains and had a trip that was even more visual than mushrooms but however did have some vasoconstrictive effects. He had profound closed and open eyed visuals and found it way more lucid than morning glory or hbwr seeds. He said that it was the best entheogen he had ever consumed bar-none, liking it even better than mushrooms.
Don't forget that decades ago, Jonathan Ott, Bigwood and Neeley each consumed from 7.5mg to 10mg of ergonovine (the only water soluble alkaloid in "the deadly" claviceps purpurea ergot, besides trace amounts of lsa) and all of them experienced closed eye geometrics in motion and constantly changing...however, it also caused significant vasoconstriction at that dosage level. The vasoconstriction was so painful in the legs, that they were unable to walk on the beach. It was debilitating
.....now perhaps we could get rid of the vasoconstriction of ergonovine? I believe it is possible and very easy to do. I believe that ergonovine is a dual-purpose medicine, being very valuable in child birth in its normal form...however it can in theory be turned into a very powerful entheogen by adducting an acetaldehyde molecule onto the indole-nitrogen position (the bottom of the ring, NOT the top indole-nitrogen amide position.) The indole adducts paper I found states that stable acetaldehyde adducts can attach at this position under the right mixing conditions and remain there, causing a new pharmacological creation to be created.
Let's not forget that ergot is nothing more than mushrooms that are so small that they can only be seen with a microscope.
Now, if we could get rid of the vasoconstriction that ergonovine causes at psychedelic doses (7.5 to 10mg)...then we would end up with a molecule that looks very very similar to sansert (prescription medicine) that is very psychedelic with profound lsd like activity at the 20mg and up level.
Jonathan Ott has said that 20mg of sansert is the equivalent of 100ug of LSD, and that 40mg of sansert is the equivalent of 200ug of LSD. there are several written reports of profound LSD like activity from the prescription sansert at the 20mg level (equivalent to 5 of the 4.5mg pills, or 10 of the 2mg pills). Sandoz discontinued sansert in the u.s. and now it is only prescribed in Canada. Shulgin has also written about this in tihkal, see the lsd section and look for sansert.
The reason that Sansert is able to remain just as psychedelic as ergonovine without having the vasoconstriction of ergonovine is simply because scientist found that adding a methyl group (CH3) onto the indole-nitrogen position reduces the vasoconstriction considerably while keeping the psychedelic effects intact.
now, I have a theory that by adding a cold water extraction of ergonovine to sherry wine (has the highest level of acetaldehyde of all the wines) and simply spinning the mixture in the fridge for 1 to 2 days will end up causing acetaldehyde (CH3CH0) in the wine to join and form a stable acetaldehyde group at the indole-nitrogen position of ergonovine....and then all the sudden you have a very new created psychedelic molecule....without hardly any of the vasoconstriction.....this is what I believe was the sacred drink that was consumed at Eleusis in ancient Greece for over 2000 years....it was simply this newly created psychedelic molecule that looks very very similar to our modern day sansert (available only by prescription from canada) that causes profound LSD like effects at the 20mg level.
the adducts paper I found on-line years ago clearly states that STABLE acetaldehyde adducts will form on the indole-nitrogen position (the bottom ring) of indoles....this happens at over 80% yield when mixing alcohol/acetaldehyde/water with the indole over a 12 to 24 hour period.
Not only that, but adding acidic molecules onto the indole-nitrogen position also cause the new psychedelic molecule to have even stronger psychedelic effects along with DECREASED anxiety and more relaxation. Remember ALD-52? It is simply LSD with a COCH3 attachment at the indole-nitrogen position.
How about it then? In theory, Lets take ergonovine and add an acetaldehyde molecule from the sherry wine to the indole-nitrogen position to create a new psychedelic molecule that is not only stronger, but has way less vasoconstriction, much reduced anxiety and more relaxation. It is very simple to do in theory. All the sudden you have something that resembles sansert which causes profound LSD like effects at the 10mg level (equal to 100ug of LSD).