Goran.Hrsak
Holofractale de l'hypervérité
- Inscrit
- 30/3/06
- Messages
- 2 454
Natural drugs contain alchaloid and chemical one doesnt.Of course you can sintetise alchaloids but I am speaking from the begining of difference 8)
Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Some fascinating studies have been done in Germany where the metabolically active mycelium of some Psilocybe species have been administered diethyltryptamine as a potential diet component. Normally, this mushroom species dutifully converts N,N-dimethyltryptamine (DMT) to psilocin, by introducing a 4-hydroxyl group into the molecule by something that is probably called an indole 4-hydroxylase by the biochemists. You put DMT in, and you get 4-hydroxy-DMT out, and this is psilocin. Maybe if you put Mickey Mouse in, you would get 4-hydroxy-Mickey Mouse out. It is as if the mushroom psyche didn't really care what it was working with, it was simply compelled to do its sacred duty to 4-hydroxylate any tryptamine it came across. It was observed that if you put N,N-diethyltryptamine (DET, not a material found in nature) into the growing process, the dutiful and ignorant enzymes would hydroxylate it to 4-hydroxy-N,N-diethyltryptamine (4-HO-DET) a potent drug also not known in nature. This is the title drug of this commentary. What a beautiful burr to thrust into the natural versus synthetic controversy. If a plant (a mushroom mycelium in this case) is given a man-made chemical, and this plant converts it, using its natural capabilities, into a product that had never before been known in nature, is that product natural? What is natural? This is the stuff of many long and pointless essays.
Alexander Shulgin, TiHKAL, 4-HO-DET Entry
forest a dit:with mdma and speed, afterwards i can't smile, like all my happyness is used up. with shrooms i feal great afterwards and do nothing but smile.
HeartCore a dit:Although I agree with most you say, I dont consider MDMA a mind narrowing drug.
Tsasil a dit:After a nice evening of MDMA I don't feel down or anything. A MDMA trip can be as rewarding as shrooming for me. For the sake of the discussion I didn't want to go there.
Even the mid-week downer after MDMA doesn't do any damage to the experience. It's just part of the effect, like puking after eating mescaline.
Tsasil a dit:HeartCore a dit:Although I agree with most you say, I dont consider MDMA a mind narrowing drug.
Me neither actually, and after a nice evening of MDMA I don't feel down or anything. A MDMA trip can be as rewarding as shrooming for me. For the sake of the discussion I didn't want to go there.
Even the mid-week downer after MDMA doesn't do any damage to the experience. It's just part of the effect, like puking after eating mescaline.
Brewmaster a dit:I don't know anything about pihkal or if you've ever done mescaline yourself, but it shouldn't make you sick. Especially not synthetic mesc ( ie microdots ).