Rumors for better highs?

[JamBar]

I've heard rumors about eating/drinking certain fruits/juices before consuming cannabis for better highs. Does anyone know what I'm talking about or will these just continue to be rumors? :?: :? :?:

 

[LsDxMdma]

consuming grapefruit juice(not o-j) before one consumes opiates or mdma(and a few other chemicals) and drinking it while on the 'chemical' , will enhance the high and extend the duration!! im not sure about cannabis!

edit**

here is a topic i posted recently pretaining to the same thing! except with lsa.

http://www.psychonaut.com/index.php?opt ... 35&lang=en

 

[GOD]

How / why should it work ?

 

[JamBar]

How / why should it work ?

I don't know. That's why I'm asking. Ha ha. :!:

 

[GOD]

Its another myth . Web shit .

 

[LsDxMdma]

wiki--
Grapefruit juice, and grapefruit in general, is a potent inhibitor of the intestinal cytochrome P450 enzyme CYP3A4, which can impact the metabolism of a variety of drugs, increasing their bioavailability when administered orally.


Drugs that may be affected include oxycodone, midazolam, ciclosporin, lovastatin, methadone, dextromethorphan, simvastatin, pravastatin, felodipine, sildenafil (Viagra) and caffeine, as well as a number of antihistamines including astemizole and terfenadine. [10]

An easy way to tell if a medication may be affected by grapefruit juice is by researching whether another known CYP3A4 inhibitor drug is already contraindicated with the active drug of the medication in question. Examples of such known CYP3A4 inhibitors include cisapride (Propulsid), erythromycin, itraconazole (Sporanox), ketoconazole (Nizoral), and mibefradil (Posicor)[citation needed].

 

[Ultima]

well, im not sure if this is actually true, but i find that taking 2-3 multi vitamins 20-30 min before smoking helps the high. (if it doesnt actually work, its a reallly good placibo)

 

[Meduzz]

increasing their bioavailability when administered orally.

So it would just be like taking more?

Roll fatter joints :wink:

 

[ophiuchus]

iis there any foundation for things like OJ,grapefruit, etc to intensify a trip(ie mushrooms, acid, mdma?

-new moderator note- Sorry adrian, I accidentally hit "edit" instead of quote on your post. Oops.

 

[JamBar]

Yeah I tried to find some information about this online and found nothing. I'm going to agree with the majority and say this rumor is false. 8)

 

[st.bot.32]

iis there any foundation for things like OJ,grapefruit, etc to intensify a trip(ie mushrooms, acid, mdma?

I thought that urban legend says vitamin c supposed to bring you down from a trip faster, cause your body to metabolize it faster?

Either way, this doesn't work for me at all, i often drink lots of OJ on trips just because i like drinking fruit juice.. and it has never noticeably shortened or lengthened my trips even if i drink it all night..

 

[Nomada]

Vibrant body energy is the only thing I find strengthens the trip--being healthy. deep oxygenation, nutrition: inside streams and digestive system, muscles' energy activated, focused mind.

 

[st.bot.32]

Vibrant body energy is the only thing I find strengthens the trip--being healthy. deep oxygenation, nutrition: inside streams and digestive system, muscles' energy activated, focused mind.

I like to go for a long walk during comeup.

 

[Mr.Smith]

.

 

[significationof?!?]

5-htp might or might not help (as in "at least placebo"). Look it up, there's info everywhere... just don't go crazy with serotonin precursors.

But really, the obvious: smoke less often, but more when you do.

 

[Psychoid]

Taking 5-htp to enhance weed's high, although efficient and pleasant, is not a good idea. I'm talking from my experience. Doing it once or twice can't do much harm though if you're really curious.

 

[IAmTheNight]

Taking 5-htp to enhance weed's high, although efficient and pleasant, is not a good idea. I'm talking from my experience. Doing it once or twice can't do much harm though if you're really curious.

I don't see why 5-htp would have any effect on the cannabis high.
It doesn't work on the serotinin receptors.

 

[significationof?!?]

I know. But the 5-htp's subtle effects may (or may not, I didn't double-blind placebo it) add in something to the high.
I did feel a slight difference... hard to put my finger on it now.

 

[Psychoid]

When I took 5-HTP before smoking I'd feel more awake, more energic and more euphoric. Music appreciation would be increased too. I'd say it had a slight similarity with MDMA, but not comparable in terms of intensity.
And THC does interact with serotonin.

(And I maintain that it is nasty doing this regularly)

 

[significationof?!?]

M'kay then how do cannabinoids interact with serotonin? You piqued my curiosity.