receptors
- Auteur de la discussion robhR
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itsscience
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From birth.
IJesusChrist
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???
"Drug receptors" are the same receptors as "Sober receptors"...
Can you be a little less vague in the question? There is a cannabinoid receptor in the brain - a holy grail for pot smokers. But then it was found the brain actually has endogenous cannabinoids, which just means THC is similar to one of our neural communicators.
It is interesting however, that LSD and psilocybin and DMT activate the same receptors as serotonin, dopamine, and the group, BUT, they actually have a different pathway, and thusly a different response.
The old picture was that we had "triangle", "square" and "circle" receptors (to make this elementary). Only "triangle" compounds could fit in a "triangle" receptor, and square in square, etc... Which is true. However, it was found that a Red triangle (LSD) can fit into a Blue triangle receptor (for serotonin) and activate it in a very different manner than that of the blue triangle (serotonin).
This is a HUGE breakthrough for the neuroscience of psychodelics!!! And was only recently discovered, in fact I think it is still in the psychonautical news section front page - go check it out.
"Drug receptors" are the same receptors as "Sober receptors"...
Can you be a little less vague in the question? There is a cannabinoid receptor in the brain - a holy grail for pot smokers. But then it was found the brain actually has endogenous cannabinoids, which just means THC is similar to one of our neural communicators.
It is interesting however, that LSD and psilocybin and DMT activate the same receptors as serotonin, dopamine, and the group, BUT, they actually have a different pathway, and thusly a different response.
The old picture was that we had "triangle", "square" and "circle" receptors (to make this elementary). Only "triangle" compounds could fit in a "triangle" receptor, and square in square, etc... Which is true. However, it was found that a Red triangle (LSD) can fit into a Blue triangle receptor (for serotonin) and activate it in a very different manner than that of the blue triangle (serotonin).
This is a HUGE breakthrough for the neuroscience of psychodelics!!! And was only recently discovered, in fact I think it is still in the psychonautical news section front page - go check it out.
itsscience
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taking drugs does not cause your cells to grow new receptors to interact with the drugs.
Receptors are essentially catcher's mitts sticking out from the cell and, due to their shape, they catch certain molecules and allow those molecules to interact with the cell. Different receptors have different shapes and so catch different molecules. It just so happens that the shape of the active molecule(s) in some drugs have a sufficiently similar structure to other molecules (e.g serotonin and LSD using IJC's example) that they are also caught by the receptors.
Receptors are essentially catcher's mitts sticking out from the cell and, due to their shape, they catch certain molecules and allow those molecules to interact with the cell. Different receptors have different shapes and so catch different molecules. It just so happens that the shape of the active molecule(s) in some drugs have a sufficiently similar structure to other molecules (e.g serotonin and LSD using IJC's example) that they are also caught by the receptors.
Jahvisions
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You are just saying something itsscience.
The amount of recepters can increase of decrease by taking substances, this mechanism is already known for ages.
http://en.wikipedia.org/wiki/Downregula ... regulation
The amount of recepters can increase of decrease by taking substances, this mechanism is already known for ages.
http://en.wikipedia.org/wiki/Downregula ... regulation
Jahvisions
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correction :to clarify, the receptors dont change, so new types of receptors will not form, but new receptors(from the same type) can be formed.
Yo robhR, if you want to get a better picture of what drugs do in the brain check out this link: http://www.jellinek.nl/brain/index.html
It explains in clear language and animations what's going on in your brain, both when sober and on drugs. It provides you with a visual picture of how various drugs and receptors interact... it's good stuff! Everytime I think 'how did that work again?' I go back to that microsite.
Happy learning!
It explains in clear language and animations what's going on in your brain, both when sober and on drugs. It provides you with a visual picture of how various drugs and receptors interact... it's good stuff! Everytime I think 'how did that work again?' I go back to that microsite.
Happy learning!
itsscience
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Jahvisions a dit:
exactly right jahvision, it has been known for ages. By "new receptors" I was referring to a new type of receptor specific to the drug taken not additional receptors of the types we already have. Our receptors, that it is the types of receptors, are with us from birth and genetically coded, taking drugs does not cause us to grow "new" receptors (new types). Sorry for the confusion.
IJesusChrist
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good site lol*fan, cleared up some gray areas, and was pretty simple.
Jahvisions
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Nice site, goos general info pretty objective.
itsscience: the moment I wrote it I already assumed you meant it that way, thats why I posted the second comment. Sorry for my quick assumption.
itsscience: the moment I wrote it I already assumed you meant it that way, thats why I posted the second comment. Sorry for my quick assumption.
itsscience
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It's Ir'e Jah 8)
Agreed, good site.
Agreed, good site.
i believe OP's referring to neurotransmitters, not receptors (a hunch due to his wording). (as most of you know) receptors and more specifically, receptor sites, are the place on the neuron where the interaction of substances occur, and the neurotransmitter is the chemical, its what causes any particular mental state.
hope that was helpful
hope that was helpful
